TO SUM (Du Yange), a famous traditional Chinese medicine doctor in Foshan, has only one daughter TO KAI-KEI (Linda Chung), who is exceptionally intelligent and shows great enthusiasm for medical skills.However, her father never expects her to be his successor because of her gender. Just as KAI-KEI is going to marry the mayor's eldest son CHONG KAI-CHO (Raymond Wong), there is an outbreak of a pandemic, duringwhich many patients including KAI-CHO suddenly die after taking medicine prescribed by TO SUM. Immediately, the mayor, CHONG TUN-YU (Poon Chi Man), orders to close down the pharmaceutical factory, leavingKAI-KEI helpless in such straitened circumstances. In the meantime, a businessman with a terminal illness, TING YAT-YUEN (Ruco Chan), raises ahostile takeover bid to buy out the pharmaceutical factory, so KAI-KEI offers to treat YAT-YUEN, trying to defend themselves against the sell-off of their assets. Also due to YAT-YUEN, KAI-KEI gets to know the retired imperial physician, SHEUNG SIK-KANG (Choi Kwok Hing), who teaches her reclusive medical skills. On the other hand, KAI-CHO's twinbrother CHONG KAI-CHUNG (Raymond Wong) just finished his study abroad and returns home. Though HUI KWAN-YEUK (Natalie Tong), a warlord's daughter, shows him affection, KAI-CHUNG secretly has a crush on his former sister-in-law. Having encountered untold hardships and difficulties, KAI-KEI and YAT-YUEN have fallen in love with each other. Unexpectedly, after the pharmaceutical factory opens for business againand everything seems to subside, YAT-YUEN's days are numbered......