KIU TIN-SENG (Ruco Chan) and LAW WAI-SHUN (Edwin Siu) are half-brothers, but fate intervenes and separates them.

Apart fromgrowing up in two different places, Hong Kong and Macau, the half-siblings have also experienced the polarizing conflicts led by drastic changes in historical events. Their mother CHOW YUK-MUI (LouiseLee) brings along the younger brother WAI-SHUN and lands in Macau as illegal immigrants. With his own efforts and help from his best friends, YIU MAN-YING (Kristal Tin) and LUNG FEI (Louis Yuen), WAI-SHUN endures hardships, overcomes challenges, and eventually finds the road to success. On the other side, TIN-SENG, who stays alone in Hong Kong to earn his own living, cuts corners by being in league with a triad leader KEUNG YUNG (Louis Cheung) and having an affair with a wealthy heir. He deeply breaks his girlfriend CHEUK CHING’s (Linda Chung) heart, ending up losing both her and fortune. Having gone through the ordeal over time, the future of their once closely related and interdependent brotherhood has become more and more unpredictable, leading the two to further diverge from one another. However, there is adeep-rooted faith in the blood-related brothers. With this faith, no matter how treacherous the tests are, they eventually reunite with each other in a new and living way……

一對親兄弟，本是同根生，命運卻令他們分開在港澳兩地，各自為夢想奮鬥打拼。一個投機取巧，好走捷徑；一個刻苦堅毅，迎難而上。兩兄弟雖然際遇不同，但仍認為每當遇上困難，只要堅持，就必然走出一條新路。在時代巨輪的洗禮下，風雲萬般變，但不變的，卻是這對兄弟間血脈相連的親情…… 偷渡不成　兄弟分離　六十年代初，周玉梅(李司棋飾)與當警察的喬森(李國麟飾)生下喬天生(陳展鵬飾)。可惜，玉梅發現喬森風流成性，傷心欲絕下帶著天生隨父親返回故鄉佛山生活。生活困苦的玉梅幸得工廠工人羅富誠(劉江飾)從旁照顧，玉梅更嫁予富誠報恩，二人亦誕下兒子羅威信(蕭正楠飾)。天生常稱香港正是實現夢想之地，令威信從小便對香港趨之若鶩。至八十年代，香港收緊抵壘政策，為怕夢想破滅，天生、威信暪著玉梅及富誠偷渡至香港，兩兄弟立志要在這片土地大展拳腳，深信只要堅持夢想便會成功。「抵壘政策」限期將至，天生抵壘成功，無奈威信卻未能趕及登記，兄弟就此相隔異地。輾轉之下，玉梅帶著威信偷渡至澳門…… 天生從警　拉攏上位天生幾經辛苦下，終找到生父喬森，怎知喬森已另組家庭，天生遂投身警界自食其力，還取得大學學歷。天生為上位不惜主動親近另一位總督察王鑑豪(鄭子誠飾)，希望投其所好表現自己，藉此在警界平步青雲！一次警隊行動中，天生遇上卓靜(鍾嘉欣飾)，還上演一幕英雄救美，是次行動令天生不但獲賞識得以升職，更與卓靜成為戀人，前景一片光明。卓靜表面生於富豪之家，實際上在家族中毫無地位，卻夢想終有一日能在時裝設計界有所作為。威信擺檔　默默耕耘玉梅和威信經特赦後取得澳門身份證，還申請富誠到澳門定居。富誠為生計與威信一同開檔謀生，威信趁機苦練烹調技術，更自立門戶開辦花生糖檔，事業初見成績。在威信悉心經營期間，他認識了旅館太子女的姚文英(田蕊妮飾)，二人因經常於威信檔口碰面，漸成好友。而手信店戇少龍飛(阮兆祥飾) 雖是威信生意上的死敵，但二人的爭執往往流於佔個口舌便宜，關係形同鬥氣街坊。威信事業開始起步同時，仍不忘繼續尋找哥哥的蹤影…… 有一次，威信獨自到香港購買原料，遇上突發事件，竟讓一對兄弟久別重逢！威信帶天生回澳門見玉梅，玉梅再見親兒，萬分激動。而天生決定帶弟弟到港發展，兩兄弟雄心壯志為夢想進發…… 兄弟重逢　反生矛盾威信到港後，一時難以適應，於是看準時機重操故業。相反，天生為求上爬，竟開始不擇手段，威信苦苦相勸，天生仍然一意孤行。兩兄弟的價值觀南轅北轍，關係不知不覺愈走愈遠…… 　　另一方面，威信其實早在澳門被卓靜的文雅氣質所吸引，只是他有自知之明，沒有表露情意。這次隨兄到港，威信始知卓靜是天生的女友。天意弄人，一次機會，令天生認識到澳門富豪之女花比奧(貝安琪飾)，面對打進上流社會的機會，他會如何抉擇？

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